HPSE and colorectal carcinoma: Anandamide 10 μM and its vehicle Tocrisolve (1 μl/ml) did not modify the CRC of U-46619 (pEC50 = 7.5 ± 0.1, n = 3; 7.5 ± 0.1, n = 4; Fig. 1) nor did they affect the basal tone of hPA rings.