The primary aim of the ‘BONDS’ (Boosting Oxytocin after trauma: Neurobiology and the Development of Stress-related psychopathology) study is to investigate the effectiveness of early intranasal oxytocin administration in reducing PTSD symptoms at 1.5 month post-trauma in trauma-exposed ED patients at increased risk of PTSD. Here, OXT is linked to post-traumatic stress disorder.