INS and type 2 diabetes mellitus: For instance, recent highly powered meta-analyses have systematically compared the association of type 2 diabetes loci with correlated glycemic (fasting glucose, fasting insulin, 2-h glucose, HbA1C, and others) and metabolic traits (BMI, lipids, and others) [24,25,64-66] in an attempt to better characterize physiologic processes underlying associations at these loci.