PROM1 and hepatocellular carcinoma: To compare the tumorigenic potential of As2O3-treated and untreated CD133+ HCC cells, we inoculated NOD/SCID mice subcutaneously with 5 × 104 CD133+ Huh7-wt cells or 2 × 105 CD133+ Hep3B-wt cells, and we found that tumor growth was inhibited by As2O3 treatment (Figure 3B).