Median serum CK-18 values progressively increased with NAFLD severity (from 169.5 (129.3/183.8) to 176 (140/190) and 180 (169.5/192.5) μIU/mL in mild, moderate, and severe steatosis, resp.; P < 0.01). The gene discussed is KRT18; the disease is metabolic dysfunction-associated steatotic liver disease.