MYF5 and chronic obstructive pulmonary disease: Other markers of muscle regeneration such as Myf5, MyoD and myogenin have been shown to be similar between COPD patients and controls (Plant et al., 2010); whereas other studies have found a difference in these factors between COPD patients and controls; and between cachetic and non-cachetic patients with COPD (Vogiatzis et al., 2010; Fermoselle et al., 2012).