NPPB and hydrops fetalis: They identified four simple clinical features (Male, history of myocardial Infarction, lung Crepitations, and oEdema: so called MICE) that could accurately triage between patients with suspected HF who should be referred for echocardiography directly and those in whom referral should depend on NT-proBNP values (sensitivity 90–96 %, specificity 58–63 %) [6].