Wnt/β-catenin signaling has an important role in communication between epithelial and stromal cells in endometrium (Tulac et al., 2003), and may have a role in endometriosis-related infertility, and/or its development through sex hormone homeostasis regulation (Matsuzaki et al., 2010; Wang et al., 2010) and fibrogenesis (Matsuzaki and Darcha, 2013). Here, PLXNA3 is linked to endometriosis.