Although a trend towards increased CCR5 density on memory CD4 T cells and an increased frequency of CCR5+/HLA-DR+ memory CD4 T cells was observed in Trichuris and Ascaris infections respectively, which is in line with previous reports [4], [7], these values varied greatly between different individuals, prohibiting conclusions on modulation of cellular susceptibility to HIV infection caused by these helminth species [12], [47]–[49]. This evidence concerns the gene CD4 and HIV infectious disease.