IGHG3 and helminthiasis: Given the distinct roles of different immunoglobulin isotypes and IgG subclasses in chronic helminth infections, and to gain a comprehensive picture of antibody reactivity from PR versus CI individuals, we analyzed IgG1, IgG3, IgG4 and IgE responses to soluble worm antigen preparation (SWAP) and a panel of schistosome antigens.