When we stratified the pooled estimates according to tumor site, there was a positive association between cyclin D1 expression and increased tumor size in tongue SCC (OR = 2.032, 95% CI = 1.200–3.441) rather than with a mixed tumor site in the oral cavity (OR = 1.431, 95% CI = 0.758–2.701) (Table 2). The gene discussed is CCND1; the disease is neoplasm.