The hereditary PHEO appears as a component of multiple endocrine neoplasia type 2 (MEN 2), von Hippel–Lindau disease (VHL), neurofibromatosis type 1 (NF1) or familial paraganglioma syndromes (caused by mutations of SDHD and SDHB genes) [3–5]. This evidence concerns the gene SDHD and von Hippel-Lindau disease.