Recently, it has been shown that, similarly to cancer-associated TF-Ag, NG2 proteoglycan produced by pericytes mediates Gal-3 translocation to and clustering at the endothelial cell membrane followed by the mobilization of endothelial α3β1 integrin, which physically interacts with Gal-3 scaffolds [28]. This evidence concerns the gene LGALS3 and cancer.