IGHG3 and malaria: Specifically, the prevalence of positive IgG1 responses was lower in the early exposure group compared to the late exposure and control groups (13 vs 28%, 28%, respectively; Chi2 p = 0.0248), and similarly for levels of IgG3 (linear regression model unadjusted p = 0.0284, adjusted for prior malaria p = 0.0343).