PROS1 and hyperinsulinemic hypoglycemia, familial, 4: Briefly, we also found that lupus anticoagulant was present in 35% of DM and 33% of nDM, functional protein S deficiency in 19% and 21%, antithrombin III deficiency in 16% and 14%, functional protein C deficiency in 14% and 7%, and anticardiolipin antibodies in 9% and 7%, respectively.