Except for Col6a3 mRNA, which showed constant high levels in both age groups, the expression of collagen type IV, alpha 2 (Col4a2), fibronectin 1 (Fn1), laminin gamma 1 (Lamc1), nidogen 2 (Nid2), and podoplanin 3 (Plod 3) mRNAs was higher in the brains of young animals at day 3 post-stroke as compared to aged animals, strongly suggesting that BL and extracellular matrix (ECM) reconstruction occurs earlier in young animals. The gene discussed is NID2; the disease is Stroke.