On the other hand, an early onset subgroup displayed a lateralized decrease in VEN number in the right ACC: the protein DISC1, involved in schizophrenia, is preferentially expressed in VENs, and the younger the age of onset of schizophrenia, the lower is the density of VENs in the right ACC (Brüne et al., 2010). This evidence concerns the gene DISC1 and schizophrenia.