Like Nox2, Nox1 is broadly expressed in a variety of cell types, including vascular smooth muscle cells, endothelial cells, uterus, placenta, prostate, osteoclasts, and retinal pericytes, as well as in several cell lines such as the colon tumor cell lines Caco2 and HT29 and the pulmonary epithelial cell line A549 [7, 9, 15]. The gene discussed is NOX1; the disease is colonic neoplasm.