Moreover, the proteome in the present study included several laryngeal cancer-associated blood markers identified in previous studies, such as CAT, IL6, IL8, S100A9, PFN1, HSPA1A, MMP2, MMP3, KRT19, SERPINB3, PRDX3, and LGALS3BP. Here, SERPINB3 is linked to laryngeal carcinoma.