In addition, no differences were found in the expression of MMP1, MMP3, MMP9, MMP13, MMP14, MMP16, TIMP1, or TIMP3, despite the fact that several authors have reported the increased expression of these proteases and their inhibitors in GC, at both mRNA and protein levels [11, 17, 35, 39, 43]. This evidence concerns the gene MMP16 and gastric cancer.