In this study the suggested tumor vascular phenotype in the Th-ALKF1174L/Th-MYCN model, which hinders the delivery of erythrocytes and causes a significantly slower R2*, may result in increased tumour hypoxia in the Th-ALKF1174L/Th-MYCN model compared with the Th-MYCN model. Here, MYCN is linked to neoplasm.