However, in both Ad-eNOS and Ad-LacZ infected mouse livers, microvascular (small fat droplets that does not displace the nucleus) and macrovesicular (large fat droplets that displaces the nucleus to the edge of the cell) steatosis, which was detected by 6 hrs after reperfusion, became remarkable with 24 hrs of reperfusion. The gene discussed is NOS3; the disease is steatosis.