In line with our observations, several abnormalities of non-MSC hematopoietic and endothelial precursor cells in CKD have been reported, including a reduced capacity for in vitro proliferation in adherent bone marrow progenitor cells [27], genomic damage to CD34+ hematopoietic progenitor cells [28], premature aging of circulating T cells [29] and functional impairment (reduced number in peripheral blood, reduced proliferation capacity in vitro) of endothelial precursor cells [30], [31]. The gene discussed is CD34; the disease is chronic kidney disease.