In agreement, mice with a PD-like phenotype fed on an n-3 PUFAs diet for 2–12 months showed significant protection against the decline in dopamine and dopamine transporter mRNA levels when compared to controls, in response to the PD-inducing drug 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine (MPTP) [146]. Here, SLC6A3 is linked to Parkinson disease.