CRP and diabetes mellitus: <2 of: hypertension risk (clinic BP > 130/85 mmHg, or hypertension diagnosis, or use of anti-hypertensive medication); diabetes risk (HbA1c > 6%); low-grade inflammation (CRP ≥ 3 mg L−1); adverse HDL-cholesterol profile (<1.03 mmol L−1 in men and <1.30 mmol L−1 women); adverse triglycerides (≥1.7 mmol L−1).BMI ≥ 30 kg m−2