Additional GWAS studies focusing on NAFLD phenotypes defined with different approaches have also identified more risk alleles in NCAN, PPP1R38, GCKR, LYPLAL1, FDFT1, COL13A1, LTBP3, EFCAB4B, ZP4, PZP and DDX60L/PALLD genes [16,17]. The gene discussed is ZP4; the disease is metabolic dysfunction-associated steatotic liver disease.