Among 5040 RA patients with episodes of herpes zoster in the German biotherapy registry, TNF inhibitors were reported to be administered in 3266 patients, among which IFX was reported in 591, as compared to 1774 patients without TNF inhibitors, concluding that TNF inhibitors were significantly associated with herpes zoster (hazards ratio: 2.24) [22]. Here, TNF is linked to rheumatoid arthritis.