FOSL1 and colorectal carcinoma: Transcriptional induction and post-translational stabilization of FRA1 by oncogenic RAS-ERK signaling increases the relative abundance of FRA1 containing AP-1 dimers, which has been causally linked enhanced migration and invasion of CRC and multiple other carcinoma cell types, including breast, lung, bladder, head and neck, thyroid and brain [6], [23]–[34].