Two other proteins associated with primary cilium function colocalized with Smo and glutamylated tubulin foci in CML cells (Fig. 5D & Fig. S5): IFT88, a component of intraflagellar transport normally found on the ciliary axoneme [32], and Arl13b, a small GTPase found in the ciliary membrane [33]. This evidence concerns the gene SMO and chronic myelogenous leukemia, BCR-ABL1 positive.