Mice inoculated with MDA RKIP had a 1.4-fold reduction in tumor mass (p<0.002), MDA si175 RKIP a 1.2-fold (p<0.008) and MDA STAT3 a 1.4-fold (p<0.002) increase in tumor mass when compared to MDA EV (Fig. 5D). Here, STAT3 is linked to neoplasm.