Previous studies show that HSP members are implicated in tumorigenesis, including tumor suppressors HLJ1 (DNAJB4), Tid1 (DNAJA3), DNAJC25, radio-resistance factor HDJ2 (DNAJA1) and other tumor-related members such as DNAJB6, DNAJC12, DNAJC1, DNAJC12, DNAJC15 [14]–[17]. The gene discussed is DNAJC12; the disease is neoplasm.