OLR1 and Huntington disease: The significant correlation between plasma OxLDL and proteinuria observed in the present work, as well as the concomitant activation of LOX-1 and TGFβ signaling pathways in vivo and the direct interaction between LOX-1 and TGFβ secretion in vitro, implicate OxLDL in the HD-induced fibrosis and tissue remodeling observed as early as 3 months after renal transplantation.