After removing rs7901695, the hazard ratio (HR) for incident diabetes was only slightly attenuated in each cohort, with HR=1.28 (95% CI, 1.06–1.54; P=0.025) in ARIC, HR=2.24 (95% CI, 1.58–3.16; P<0.0001) in FOS and HR=1.18 (95% CI, 0.85–1.66; P=0.32) in MESA. This evidence concerns the gene FOS and diabetes mellitus.