The higher BSV of postoperative CD133 mRNA in the PBMCs of patients with GC was also associated with the lymphatic vessel invasion (P = 0.005), the deeper invasion (P < 0.001), the lymph nodes metastasis (LNM) (P = 0.001), and the later stages of TNM (P < 0.001) (Table 3). The gene discussed is PROM1; the disease is benign neoplasm.