This is consistent with the observation that β-adrenergic stimulation of myocytes isolated from mice overexpressing CaMKII (Sag et al., 2009) or subjected to TAC-induced HF (Toischer et al., 2013) increased the number of DADs, which were largely prevented by either ranolazine or AIP (Toischer et al., 2013). The gene discussed is CAMK2G; the disease is hydrops fetalis.