MUC1 and pachyonychia congenita: We utilized three distinct murine PC cell lines, denoted as KCM, KCKO, and Pan02, derived from spontaneous PC arising from genetic models (LSL-KRASG12D × P48-Cre × MUC1 and LSL-KRASG12D × p48-Cre, respectively) or tumors arising from 3-methylcholanthrene carcinogenesis (Pan02) [23].