Previous studies have shown that clinical risk factors such as age, gender, body mass index (BMI), family history of T2D, systolic blood pressure, high-density lipoprotein cholesterol level, triglycerides level, insulin secretion and fasting plasma glucose are risk predictors for T2D [7], although their predictive ability may have been influenced by study design and population [8]. This evidence concerns the gene INS and type 2 diabetes mellitus.