Additionally, a lookup of large GWAS studies of cardiovascular and cerebrovascular disease, identified many of our most significant chromosome 6 findings in a meta-analysis for blood lipids [28], with rs2274517 being the most significant result (p = 1.37×10−4), suggesting that GNMT may play a broader role in risk traits for CVD beyond tHcy measures. This evidence concerns the gene GNMT and cerebrovascular disorder.