ERVW-1 and HIV infectious disease: While testing the safety and immunogenicity of SERV-K Env & Gag, and human LINE-1 in rhesus macaques to enable further development of ERE-targeting strategies in both cancer and HIV infection, we reasoned that the rhesus macaque SIV challenge model might also be suitable for assessing their efficacy as stable surrogate targets marking SIV-infected cells.