For example, the lncRNA MALAT1 modulates SR splicing factor phosphorylation [116], whereas miR-188-5p which is complementary to the PD-induced lncRNAs targets the alternative splicing regulatory factor SFRS1 (SF2/ASF) [117] (which we previously reported as modified in PD patients through exon microarray analysis). This evidence concerns the gene MALAT1 and Parkinson disease.