THBS1 and myocardial infarction: Stromelysin-1 (matrix metalloproteinase-3 [MMP3]), neutrophil elastase (also named as Human leukocyte elastase, HLE), thrombospondin-1 (TSP1), and fibronectin [35] increased in plasma from patients post-MI [36], [37], [38], [39], [40].