CD8A and infection: In the case of other models of chronic infection in which the pathogens do not disseminate to, or disappear from, the thymus [e.g. polyoma virus infection or more than 30 days after lymphocytic choriomeningitis virus (LCMV) clone 13 infection], newly recruited virus-specific CD8+ T cells can be primed and differentiate into functional memory CD8+ T cells [5], [6].