Tumors with NS positivity showed a higher frequency of ER positivity, HER2 positivity, and p53 positivity (P = 0.050, P = 0.021, and P = 0.031, respectively), whereas NS expression status was not correlated with tumor size, lymph node metastasis, distant metastasis, tumor nuclear grade, or PgR positivity. The gene discussed is TP53; the disease is neoplasm.