The positive rates of p53 and Ki-67 were highest in the poor histological grade group (61.54 and 84.62%, respectively), p53 expression was correlated with tumor size and histological grade (χ2=4.7314, P=0.0300 and χ2=4.6443, P=0.0310, respectively) and Ki-67 expression was correlated with histological grade (χ2=5.5000, P=0.0190). This evidence concerns the gene MKI67 and neoplasm.