C1QC and tuberculosis: While our study also found an increase in the expression of some interferon inducible genes as well as FCGR1B and CD64 (data not shown), the ROC analysis revealed that C1qC mRNA expression alone in PBMC can distinguish active TB from HC with a sensitivity of 83% and specificity of 89%, and active TB from LTBI with a sensitivity of 74% and specificity of 82%, respectively.