The corresponding ORs for high blood pressure, high TG, low HDL cholesterol, high WHR and high urine ACR according to baseline DPP4 activity were 3.66, 2.30, 2.84, 2.53 and 1.90, according to baseline active GLP-1 were 0.51, 0.19, 0.29, 0.38 and 1.10 respectively (Table S1-S2 in File S1). Here, GCG is linked to hypertensive disorder.