DPP4 and metabolic syndrome: Lamers et al. [6]have proved that enlargement of visceral adipocytes and adipose tissue inflammation enhance the release of DPP4 from the fat cell to circulation, moreover, they found that circulating DPP4 concentrations correlated with various classic markers for the metabolic syndrome, namely, waist circumference, BMI, plasma triglycerides, HOMA-IR and fat cell volume.