PDGFD and neoplasm: Compared to the their adjacent normal tissues, 32 of 58 (55.2%, Table 1) endometrial cancer samples presented the over-expression of PDGF-D (p < 0.001, Figures 1 and 2A); moreover, we found that high level of PDGF-D was related to late tumor stage (p = 0.003, Figure 2B), deep myometrium invasion (p < 0.001, Figure 2C) and lympha vascular space invasion (p = 0.0063, Figure 2D).