While the treatment of CXCR3-deficient mice with concanavalin A results in a decreased recruitment of IL10-producing CXCR3+ Tregs [175], CXCR3 blockade in a model for ischemia-reperfusion injury causes a reduction in intrahepatic Th1 cells [177]. This evidence concerns the gene CXCR3 and ischemia reperfusion injury.