CALCA and cancer: Our findings that hCT and sCT are close to equipotent during short-term stimulation are in line with previous work on hCT and sCT activated cAMP production; two-fold difference in an overexpressing CT(a) receptor cell line [12], equipotency in CT(a) receptor-transfected cell lines [19] and a six-fold difference in T47D cancer cells [19].