The method was applied to four phenotypes, cecum total score (CTS), spleen/body weight ratio (SBWR), mesenteric lymph node(MLN)/body weight ratio(MBWR), and secretory IgA (SIgA) level, where cecum total score was graded by using colitis-related criteria, including severity, hyperplasia, ulceration and the percentage of area involved. This evidence concerns the gene CD79A and colitis.